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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
UCHL3_HUMAN
USC-OGP 2-DE database
:
UCHL3_HUMAN
UCHL3_HUMAN
General information about the entry
View entry in simple text format
Entry name
UCHL3_HUMAN
Primary accession number
P15374
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Ubiquitin carboxyl-terminal hydrolase isozyme L3; Short=UCH-L3; EC=3.4.19.12; AltName: Full=Ubiquitin thioesterase L3;.
Gene name
Name=UCHL3
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-5
{PLATELET 4-5}
Homo sapiens (Human)
map experimental info
PLATELET_4-5
MAP LOCATIONS:
SPOT OGP-0181
:
pI=4.72; Mw=26529
SPOT OGP-0186
:
pI=4.72; Mw=26070
Cross-references
UniProtKB/Swiss-Prot
P15374; UCHL3_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
UCHL3_HUMAN
Primary accession number
P15374
Secondary accession number(s)
B2R970 Q5TBK8 Q6IBE9
Sequence was last modified on
April 1, 1990 (version 1)
Annotations were last modified on
March 15, 2017 (version 170)
Name and origin of the protein
Description
RecName: Full=Ubiquitin carboxyl-terminal hydrolase isozyme L3; Short=UCH-L3; EC=3.4.19.12; AltName: Full=Ubiquitin thioesterase L3;
Gene name
Name=UCHL3
Encoded on
Name=UCHL3
Keywords
3D-structure
;
Complete proteome
;
Cytoplasm
;
Hydrolase
;
Phosphoprotein
;
Protease
;
Reference proteome
;
Thiol protease
;
Ubl conjugation pathway
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M30496; AAA36791.1
; -; mRNA
EMBL
BT019359; AAV38166.1
; -; mRNA
EMBL
CR456855; CAG33136.1
; -; mRNA
EMBL
AK313665; BAG36417.1
; -; mRNA
EMBL
AL137244; CAI12419.1
; -; Genomic_DNA
EMBL
CH471093; EAW80542.1
; -; Genomic_DNA
EMBL
BC018125; AAH18125.1
; -; mRNA
CCDS
CCDS9453.1; -
; .
PIR
A40085; A40085
; .
RefSeq
NP_001257881.1; NM_001270952.1
; .
RefSeq
NP_005993.1; NM_006002.4
; .
UniGene
Hs.162241; -
; .
UniGene
Hs.674394; -
; .
PDB
1UCH; X-ray
; 1.80 A; A=1-230
PDB
1XD3; X-ray
; 1.45 A; A/C=1-230
PDBsum
1UCH; -
; .
PDBsum
1XD3; -
; .
ProteinModelPortal
P15374; -
; .
SMR
P15374; -
; .
BioGrid
113194; 87
; .
DIP
DIP-29135N; -
; .
IntAct
P15374; 11
; .
MINT
MINT-2863935; -
; .
STRING
9606.ENSP00000366819; -
; .
BindingDB
P15374; -
; .
ChEMBL
CHEMBL6195; -
; .
GuidetoPHARMACOLOGY
2427; -
; .
MEROPS
C12.003; -
; .
iPTMnet
P15374; -
; .
PhosphoSitePlus
P15374; -
; .
DMDM
136682; -
; .
OGP
P15374; -
; .
REPRODUCTION-2DPAGE
IPI00011250; -
; .
EPD
P15374; -
; .
MaxQB
P15374; -
; .
PaxDb
P15374; -
; .
PeptideAtlas
P15374; -
; .
PRIDE
P15374; -
; .
DNASU
7347; -
; .
Ensembl
ENST00000377595; ENSP00000366819
; ENSG00000118939; .
GeneID
7347; -
; .
KEGG
hsa:7347; -
; .
UCSC
uc001vjq.5; human
; .
CTD
7347; -
; .
DisGeNET
7347; -
; .
GeneCards
UCHL3; -
; .
HGNC
HGNC:12515; UCHL3
; .
HPA
CAB037139; -
; .
HPA
CAB037208; -
; .
HPA
HPA019678; -
; .
MIM
603090; gene
; .
neXtProt
NX_P15374; -
; .
OpenTargets
ENSG00000118939; -
; .
PharmGKB
PA37162; -
; .
eggNOG
KOG1415; Eukaryota
; .
eggNOG
ENOG4111HNA; LUCA
; .
GeneTree
ENSGT00510000046640; -
; .
HOGENOM
HOG000182400; -
; .
HOVERGEN
HBG075483; -
; .
InParanoid
P15374; -
; .
KO
K05609; -
; .
OMA
VYGMEPE; -
; .
OrthoDB
EOG091G0LBS; -
; .
PhylomeDB
P15374; -
; .
TreeFam
TF316166; -
; .
BRENDA
3.4.19.12; 2681
; .
Reactome
R-HSA-5689603; UCH proteinases
; .
Reactome
R-HSA-8866652; Synthesis of active ubiquitin: roles of E1 and E2 enzymes
; .
SABIO-RK
P15374; -
; .
ChiTaRS
UCHL3; human
; .
EvolutionaryTrace
P15374; -
; .
GeneWiki
UCHL3; -
; .
GenomeRNAi
7347; -
; .
PRO
PR:P15374; -
; .
Proteomes
UP000005640; Chromosome 13
; .
Bgee
ENSG00000118939; -
; .
CleanEx
HS_UCHL3; -
; .
ExpressionAtlas
P15374; baseline and differential
; .
Genevisible
P15374; HS
; .
GO
GO:0005737; C:cytoplasm
; IBA:GO_Central; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005634; C:nucleus
; IDA:HPA; .
GO
GO:0019784; F:NEDD8-specific protease activity
; TAS:Reactome; .
GO
GO:0008233; F:peptidase activity
; IDA:UniProtKB; .
GO
GO:0004843; F:thiol-dependent ubiquitin-specific protease activity
; IBA:GO_Central; .
GO
GO:0036459; F:thiol-dependent ubiquitinyl hydrolase activity
; TAS:Reactome; .
GO
GO:0043130; F:ubiquitin binding
; IDA:UniProtKB; .
GO
GO:0030163; P:protein catabolic process
; IDA:UniProtKB; .
GO
GO:0016579; P:protein deubiquitination
; IBA:GO_Central; .
GO
GO:0016567; P:protein ubiquitination
; TAS:Reactome; .
GO
GO:0006511; P:ubiquitin-dependent protein catabolic process
; IEA:InterPro; .
Gene3D
3.40.532.10; -
; 1; .
InterPro
IPR001578; Peptidase_C12_UCH
; .
PANTHER
PTHR10589; PTHR10589
; 1; .
Pfam
PF01088; Peptidase_C12
; 1; .
PRINTS
PR00707; UBCTHYDRLASE
; .
PROSITE
PS00140; UCH_1
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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