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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: UCHL3_HUMAN




USC-OGP 2-DE database:  UCHL3_HUMAN


UCHL3_HUMAN


General information about the entry
View entry in simple text format
Entry nameUCHL3_HUMAN
Primary accession numberP15374
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Ubiquitin carboxyl-terminal hydrolase isozyme L3; Short=UCH-L3; EC=3.4.19.12; AltName: Full=Ubiquitin thioesterase L3;.
Gene nameName=UCHL3
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-5 {PLATELET 4-5}
Homo sapiens (Human)
PLATELET_4-5
  map experimental info
 
PLATELET_4-5

MAP LOCATIONS:
pI=4.72; Mw=26529
pI=4.72; Mw=26070

Cross-references
UniProtKB/Swiss-ProtP15374; UCHL3_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameUCHL3_HUMAN
Primary accession numberP15374
Secondary accession number(s) B2R970 Q5TBK8 Q6IBE9
Sequence was last modified on April 1, 1990 (version 1)
Annotations were last modified on March 15, 2017 (version 170)
Name and origin of the protein
DescriptionRecName: Full=Ubiquitin carboxyl-terminal hydrolase isozyme L3; Short=UCH-L3; EC=3.4.19.12; AltName: Full=Ubiquitin thioesterase L3;
Gene nameName=UCHL3
Encoded onName=UCHL3
Keywords3D-structure; Complete proteome; Cytoplasm; Hydrolase; Phosphoprotein; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM30496; AAA36791.1; -; mRNA
EMBLBT019359; AAV38166.1; -; mRNA
EMBLCR456855; CAG33136.1; -; mRNA
EMBLAK313665; BAG36417.1; -; mRNA
EMBLAL137244; CAI12419.1; -; Genomic_DNA
EMBLCH471093; EAW80542.1; -; Genomic_DNA
EMBLBC018125; AAH18125.1; -; mRNA
CCDSCCDS9453.1; -; .
PIRA40085; A40085; .
RefSeqNP_001257881.1; NM_001270952.1; .
RefSeqNP_005993.1; NM_006002.4; .
UniGeneHs.162241; -; .
UniGeneHs.674394; -; .
PDB1UCH; X-ray; 1.80 A; A=1-230
PDB1XD3; X-ray; 1.45 A; A/C=1-230
PDBsum1UCH; -; .
PDBsum1XD3; -; .
ProteinModelPortalP15374; -; .
SMRP15374; -; .
BioGrid113194; 87; .
DIPDIP-29135N; -; .
IntActP15374; 11; .
MINTMINT-2863935; -; .
STRING9606.ENSP00000366819; -; .
BindingDBP15374; -; .
ChEMBLCHEMBL6195; -; .
GuidetoPHARMACOLOGY2427; -; .
MEROPSC12.003; -; .
iPTMnetP15374; -; .
PhosphoSitePlusP15374; -; .
DMDM136682; -; .
OGPP15374; -; .
REPRODUCTION-2DPAGEIPI00011250; -; .
EPDP15374; -; .
MaxQBP15374; -; .
PaxDbP15374; -; .
PeptideAtlasP15374; -; .
PRIDEP15374; -; .
DNASU7347; -; .
EnsemblENST00000377595; ENSP00000366819; ENSG00000118939; .
GeneID7347; -; .
KEGGhsa:7347; -; .
UCSCuc001vjq.5; human; .
CTD7347; -; .
DisGeNET7347; -; .
GeneCardsUCHL3; -; .
HGNCHGNC:12515; UCHL3; .
HPACAB037139; -; .
HPACAB037208; -; .
HPAHPA019678; -; .
MIM603090; gene; .
neXtProtNX_P15374; -; .
OpenTargetsENSG00000118939; -; .
PharmGKBPA37162; -; .
eggNOGKOG1415; Eukaryota; .
eggNOGENOG4111HNA; LUCA; .
GeneTreeENSGT00510000046640; -; .
HOGENOMHOG000182400; -; .
HOVERGENHBG075483; -; .
InParanoidP15374; -; .
KOK05609; -; .
OMAVYGMEPE; -; .
OrthoDBEOG091G0LBS; -; .
PhylomeDBP15374; -; .
TreeFamTF316166; -; .
BRENDA3.4.19.12; 2681; .
ReactomeR-HSA-5689603; UCH proteinases; .
ReactomeR-HSA-8866652; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; .
SABIO-RKP15374; -; .
ChiTaRSUCHL3; human; .
EvolutionaryTraceP15374; -; .
GeneWikiUCHL3; -; .
GenomeRNAi7347; -; .
PROPR:P15374; -; .
ProteomesUP000005640; Chromosome 13; .
BgeeENSG00000118939; -; .
CleanExHS_UCHL3; -; .
ExpressionAtlasP15374; baseline and differential; .
GenevisibleP15374; HS; .
GOGO:0005737; C:cytoplasm; IBA:GO_Central; .
GOGO:0005829; C:cytosol; IDA:HPA; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005634; C:nucleus; IDA:HPA; .
GOGO:0019784; F:NEDD8-specific protease activity; TAS:Reactome; .
GOGO:0008233; F:peptidase activity; IDA:UniProtKB; .
GOGO:0004843; F:thiol-dependent ubiquitin-specific protease activity; IBA:GO_Central; .
GOGO:0036459; F:thiol-dependent ubiquitinyl hydrolase activity; TAS:Reactome; .
GOGO:0043130; F:ubiquitin binding; IDA:UniProtKB; .
GOGO:0030163; P:protein catabolic process; IDA:UniProtKB; .
GOGO:0016579; P:protein deubiquitination; IBA:GO_Central; .
GOGO:0016567; P:protein ubiquitination; TAS:Reactome; .
GOGO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro; .
Gene3D3.40.532.10; -; 1; .
InterProIPR001578; Peptidase_C12_UCH; .
PANTHERPTHR10589; PTHR10589; 1; .
PfamPF01088; Peptidase_C12; 1; .
PRINTSPR00707; UBCTHYDRLASE; .
PROSITEPS00140; UCH_1; 1; .



USC-OGP 2-DE database image


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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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